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Strong Core Business, Raised Guidance Push Vertex Pharmaceuticals Higher

By
Lucas Downey
Published: Sep 11, 2026, 11:54 GMT+00:00

$514.56

-1.26%

Since 2008, Vertex Pharmaceuticals, Inc. (VRTX) shares have received 42 outlier institutional inflow signals and gained over 1,682%.

Wall Street and the stock exchange illustration
In this article:

VRTX is a biotechnology company focused on treatments for cystic fibrosis, influenza, bacterial infections, rheumatoid arthritis, cancer, inflammatory bowel disease, and neurological disorders including pain and multiple sclerosis. VRTX’s second-quarter fiscal 2027 report showed $3.3 billion in quarterly revenue (a 12% year-over-year gain), non-GAAP per-share earnings of $4.73 (a 5% jump), roughly $13.6 billion in cash and investments, and increased full-year revenue guidance to a top end of $13.2 billion.

It’s no wonder VRTX shares are up 13% so far this year – and they could rise more. MoneyFlows data shows how Big Money investors are betting heavily on the forward picture of the stock.

Vertex Pharmaceuticals Attracts Institutional Inflows

Institutional volumes reveal plenty. In 2026, VRTX has enjoyed strong investor demand, which we believe to be institutional support.

Each green bar signals unusually large volumes in VRTX shares. They reflect our proprietary inflow signal, pushing the stock higher:

VRTX shares up 32.4% in a year thanks to strong and sustained institutional inflows. Source: www.moneyflows.com

Plenty of health care names are under accumulation right now. But there’s a powerful fundamental story happening with Vertex Pharmaceuticals.

Vertex Pharmaceuticals Fundamental Analysis

Institutional support and a healthy fundamental backdrop make this company worth investigating. As you can see, VRTX has had strong sales and profits:

  • 3-year sales growth rate (+11.3%)
  • Profit margin (+32.7%)

Source: FactSet

Also, EPS is estimated to ramp higher this year by +13.2%.

Now it makes sense why the stock has been generating Big Money interest. VRTX has a track record of strong financial performance.

Marrying great fundamentals with our proprietary software has found some big winning stocks over the long term.

Vertex Pharmaceuticals has been a top-rated stock at MoneyFlows. That means the stock has unusual buy pressure and growing fundamentals. We have a ranking process that showcases stocks like this on a weekly basis.

It’s made the rare Outlier 20 inflow report 42 times since 2008, gaining 1,682%. The blue bars below show when VRTX was a top pick in the last five years…institutional support matters:

Since 2008 institutions have bought VRTX shares in big volumes 42 times, gaining 1,682%. Source: www.moneyflows.com

Tracking unusual volumes reveals the power of money flows.

This is a trait that most outlier stocks exhibit…the best of the best. Big Money demand drives stocks upward.

Vertex Pharmaceuticals Price Prediction

The VRTX action isn’t new at all. Big Money buying in the shares is signaling to take notice. Given the historical gains in share price and strong fundamentals, this stock could be worth a spot in a diversified portfolio.

Disclosure: the author holds no position in VRTX at the time of publication.

If you are a Registered Investment Advisor (RIA) or a serious investor, take your investing to the next level. MoneyFlows created 11 Frontiers indexes to help serious investors capture AI-driven themes and learn the leading stocks in each Frontier. Get started here.

About the Author

Lucas Downeycontributor

Lucas is a well-versed equity investor and educator. He currently is co-founder of research and analytics firm, MAPsignals.com, which focuses on finding outlier stocks by following the Big Money.

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