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Strong Results, Guidance Boost Eli Lilly Shares Ahead of Earnings

By: 
Lucas Downey
Eli Lilly logo, vaccine, DNA strand and trading chart

Shares of Eli Lilly and Company (LLY) rise 19,899% since Big Money bought big in 1990.

LLY is a health care giant, creating medicines for diabetes, oncology, immunology, neuroscience, and obesity, along with using advanced technologies and AI to make more treatments. The company’s second-quarter fiscal 2026 earnings report, LLY showed $23 billion in quarterly revenue (a 48% year-over-year gain) led by its Zepbound and Mounjaro products ($14.9 billion together), non-GAAP per-share earnings of $8.38 (a 32.8% annual jump), and offered annual guidance of up to $87 billion and $36.50 for revenue and EPS, respectively. The company reports again on Oct. 29.

It’s no wonder LLY shares are up 19% this year, and they could rise more. MoneyFlows data shows how Big Money investors are betting heavily on the stock.

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Institutions Buying Eli Lilly

Institutional volumes reveal plenty. In the last year, LLY has enjoyed strong investor demand, which we believe to be institutional support.

Each green bar signals unusually large volumes in LLY shares. They reflect our proprietary inflow signal, pushing the stock higher:

Line chart tracking Eli Lilly and Company (LLY) stock performance from Oct. 27, 2025, to Oct. 27, 2026, with price shown in blue. Share price ranges from about $800 to $1,300, rising sharply after June 2026; green vertical markers indicate inflows, while magenta markers indicate outflows.
Institutional investor support has pushed LLY shares up over 55% in the last year. Source: www.moneyflows.com

Plenty of health care names are under accumulation right now. But there’s a powerful fundamental story happening with Eli Lilly.

Eli Lilly Fundamental Analysis

Institutional support and a healthy fundamental backdrop make this company worth investigating. As you can see, LLY has had strong sales and earnings growth:

  • 3-year sales growth rate (+32.1%)
  • 3-year EPS growth rate (+60.6%)

Source: FactSet

Also, EPS is estimated to ramp higher this year by +39.9%.

Now it makes sense why the stock has been generating Big Money interest. LLY has a track record of strong financial performance.

Marrying great fundamentals with MoneyFlows software has found some big winning stocks over the long term.

Eli Lilly has been a top-rated stock at MoneyFlows for years. That means the stock has unusual buy pressure and growing fundamentals. We have a ranking process that showcases stocks like this on a weekly basis.

Since 1990, LLY has drawn 103 outlier inflow signals and is up 19,899%. The blue bars below show when LLY was a top pick on the Outlier 20 report in the last year…institutions keep buying:

Line-and-area stock chart tracks Eli Lilly and Company (LLY) share price from Oct 27, 2025, to Oct 27, 2026, with $800–$1,300 vertical scale. Blue price trend declines into spring, rebounds sharply during summer, and reaches roughly $1,280 in October; teal vertical markers indicate outlier inflows, while yellow denotes outlier outflows.
Since 1990, LLY has drawn 103 outlier inflow signals and gained 19,899% due to strong institutional support. Source: www.moneyflows.com

Tracking unusual volumes reveals the power of money flows.

This is a trait that most outlier stocks exhibit…the best of the best. Big Money demand drives stocks upward.

Eli Lilly Price Prediction

The LLY action isn’t new at all. Big Money buying in the shares is signaling to take notice. Given the historical gains in share price and strong fundamentals, this stock could be worth a spot in a diversified portfolio.

Disclosure: the author holds no position in LLY at the time of publication.

If you are a Registered Investment Advisor (RIA) or a serious investor, take your investing to the next level. MoneyFlows created 11 Frontiers indexes to help serious investors capture AI-driven themes and learn the leading stocks in each Frontier. Get started here.

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About the Author

Lucas Downeycontributor

Lucas is a well-versed equity investor and educator. He currently is co-founder of research and analytics firm, MAPsignals.com, which focuses on finding outlier stocks by following the Big Money.

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