Exelixis, Inc. (EXEL), an oncology-focused biopharmaceutical firm, is up 81% since a Big Money boost starting in 2021.
EXEL discovers, develops, and commercializes new treatments for hard-to-treat cancers. Its third-quarter 2025 report showed $598 million in quarterly revenue, GAAP net income of $193.6 million ($0.69 per diluted share), and increased total 2025 revenue guidance of up to $2.35 billion.
It’s no wonder EXEL shares are up 32% this year. MoneyFlows data shows how Big Money investors are once again betting heavily on the forward picture of the stock.
Institutional volumes reveal plenty. In the last year, EXEL has enjoyed strong investor demand, which we believe to be institutional support.
Each green bar signals unusually large volumes in EXEL shares. They reflect our proprietary inflow signal, pushing the stock higher:
Plenty of health care names are under accumulation right now. But there’s a powerful fundamental story happening with Exelixis.
Institutional support and a healthy fundamental backdrop make this company worth investigating. As you can see, EXEL has had strong sales and earnings growth:
Source: FactSet
Also, EPS is estimated to ramp higher this year by +11.4%.
Now it makes sense why the stock has been generating Big Money interest. EXEL has a track record of strong financial performance.
Marrying great fundamentals with our proprietary software has found some big winning stocks over the long term.
Exelixis has been a top-rated stock at MoneyFlows. That means the stock has unusual buy pressure and growing fundamentals. We have a ranking process that showcases stocks like this on a weekly basis.
It’s made the rare Outlier 20 report 15 times in the last five years, rising 81% since May 2021’s outlier inflow signal. The blue bars below show when EXEL was a top pick…Big Money keeps buying:
Tracking unusual volumes reveals the power of money flows.
This is a trait that most outlier stocks exhibit…the best of the best. Big Money demand drives stocks upward.
The EXEL action isn’t new at all. Big Money buying in the shares is signaling to take notice. Given the historical gains in share price and strong fundamentals, this stock could be worth a spot in a diversified portfolio.
Disclosure: the author holds no position in EXEL at the time of publication.
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Lucas is a well-versed equity investor and educator. He currently is co-founder of research and analytics firm, MAPsignals.com, which focuses on finding outlier stocks by following the Big Money.