Ethereum Price Forecast: ETH/BTC Golden Cross Signals Potential 250% Rally Setup

Ethereum’s native token, Ether (ETH), performance against Bitcoin (BTC) is flashing a historic signal that previously preceded one of its strongest rallies ever.

ETH/BTC Golden Cross Mirroring a 250% Rally Setup From 2020

On the ETH/BTC weekly chart, the 20-week exponential moving average (EMA) is on the verge of crossing above the 50-week EMA. This so-called Golden Cross last appeared in early 2020, just before ETH outperformed BTC by nearly 250% in the following year.

This time, the setup again coincides with ETH bouncing strongly from its multi-year accumulation zone at around 0.020–0.025 BTC, reinforcing its role as a long-term support base.

Still, ETH/BTC faces immediate hurdles. The pair is currently testing its 200-week EMA (~0.045 BTC), a level that triggered bearish rejections in both 2021 and the present move.

In the previous cycle, ETH initially failed to clear this resistance but later broke higher, accelerating its climb toward the 0.08–0.09 BTC area. A similar path may be unfolding now, though the weekly RSI’s overbought reading warns of a possible pullback before any breakout attempt.

As shown above, overbought conditions at the same time as a Golden Cross often create short-term turbulence. But the broader trend remains favorable if ETH holds its mid-term moving averages.

Ethereum’s Path Toward 0.087 BTC

Should ETH/BTC decisively break and hold above the 200-week EMA, the pair could aim for 0.06 BTC as an interim target, mirroring the first leg of the 2020–21 rally.

From there, the ultimate upside lies around 0.087 BTC, the prior cycle peak and the key resistance to watch in the months ahead.

The macro backdrop could provide the missing fuel, just like it did in 2020.

The previous 250% ETH/BTC rally took cues from DeFi tokens’ growth and loose monetary policies. Today, the pair’s growth is coming from Ethereum’s expanding ecosystem via real-world assets tokenization, institutional staking, ETF adoption, and Ethereum Treasurys.

Together, they may underpin another wave of ETH dominance if capital continues rotating from Bitcoin into the broader crypto economy.

Mega Whales Are Backing the Rally

Onchain data adds conviction to the bullish thesis. The number of Ethereum mega-whale wallets (balances over 10,000 ETH) has surged sharply in recent months, according to Glassnode.

The 30-day net change in these addresses flipped positive in mid-2025 and has since accelerated, marking one of the strongest accumulation phases since the 2020–21 bull run.

At the same time, ETH’s price is climbing toward $5,000, suggesting large players are positioning for further upside.

If this accumulation trend persists, it could provide the liquidity and confidence Ethereum needs to sustain a breakout toward 0.087 BTC — echoing the 250% “deja vu” rally setup from the last cycle.